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Working Group on New TB Drugs

Stop TB Partnership

10 Sep 2013
by Working Group

Posted in TB Drug Development, TB News

Fighting Tuberculosis With FDA Approved Hypertensive Drug Verapamil

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In a significant finding for millions of TB patients, researchers have recently shown that adjunct chemotherapy with verapamil can accelerate tuberculosis treatment in mouse model.

30 Jul 2013

EMA fails to recommend Otsuka’s Delamanid for MDR TB

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The Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) failed to recommend marketing approval for delamanid, a new drug in development for multidrug-resistant tuberculosis (MDR-TB). A letter from the Treatment Action Group criticizing this decision is included.

17 Jul 2013
by Working Group

Posted in Announcements, TB Drug Development, TB News

Sequella Acquires Exclusive Worldwide Rights to Pfizer’s Sutezolid

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Sequella today announced that it has licensed Pfizer Inc’s exclusive worldwide rights to develop and commercialize sutezolid, a Phase 2 oxazolidinone antibiotic currently in development for the treatment of tuberculosis (TB).

10 Jul 2013
by Working Group

Posted in Faces of TB, TB Drug Development, TB News

How to Combat Tuberculosis: NPR Highlights

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Yesterday, the US National Public Radio posted online two insightful pieces on tuberculosis: 1) What It Takes To Cure Drug-Resistant Tuberculosis 2) Treating The ‘Body And Soul’ In A Russian TB Prison

9 Jul 2013
by Working Group

Posted in Announcements, TB Drug Development, TB News

Otsuka Begins Paediatric MDR-TB Trials

otsuka

Enrollment has begun for a ground-breaking clinical program exploring the use of delamanid in paediatric multidrug-resistant tuberculosis (MDR-TB). Otsuka is the first company to perform a trial among this population for regulatory approval. The programme will also evaluate the bioequivalence of a dispersible formulation for use with younger children and infants.

1 Jul 2013
by Working Group

Posted in Action, TB Drug Development, TB News

TAG Releases 2013 Pipeline Report

Click here to access full report

HIV i-Base and Treatment Action Group (TAG) called on global and national leaders, research sponsors, and regulatory authorities to work together to make the best HIV, HCV, and TB drugs, diagnostics, and vaccines accessible as fast as possible, according to a report released today at the 7th International AIDS Society (IAS) Conference on HIV Pathogenesis, Treatment and Prevention in Kuala Lumpur, Malaysia.

13 Jun 2013

WHO Issues Interim Guidance on the Use of Bedaquiline to Treat

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The World Health Organization (WHO) has issued interim guidance on the use of bedaquiline, a new tuberculosis drug, for the treatment of multidrug-resistant tuberculosis (MDR-TB).

TB R&D Update: Vitamin C Kills Tuberculosis in vitro

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This week we highlight a study out of Dr. William Jacobs, Jr.’s lab showing that “vitamin C, a compound known to drive the Fenton reaction, sterilizes cultures of drug-susceptible and drug-resistant Mycobacterium tuberculosis, the causative agent of tuberculosis.” Additional links to other news and articles related to TB R&D are included.

16 Apr 2013

Medecins Sans Frontieres/Doctors Without Borders Scientific Day May 10th

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MSF Scientific Day is a unique opportunity to showcase medical and scientific research carried out in MSF programmes around the world. Presenting and debating the findings from our research is vital to improve the quality of our humanitarian programmes. There will be several topic s on tuberculosis.

16 Apr 2013
by Working Group

Posted in Announcements, market access, TB News

New Database Tracks Health Technology Innovations

Click here to check out entire database.

The Center for Health Market Innovations (CHMI) has compiled profiles on over 1,200 programs and counting. For TB innovations, the CHMI database contains 58 programs that work on TB in 33 countries.