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Working Group on New TB Drugs

Stop TB Partnership

11 Oct 2011
by Working Group

Posted in Announcements, TB News

Press Release! WHO Warns of Consequences of Underfunding TB

who-logo

The World Health Organization (WHO) reports for the first time that the number of people falling ill with tuberculosis (TB) each year is declining. New data, published today in the WHO 2011 Global Tuberculosis Control Report, also show that the number of people dying from the disease fell to its lowest level in a decade.

29 Sep 2011
by Working Group

Posted in Events, TB Drug Development, TB News

TB R&D Weekly Update: ICAAC and TB Drug Clinical Workshop

ICAAC

On September 16, the 4th International Workshop on Clinical Pharmacology of Tuberculosis Drugs was held adjacent to the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) which was held from September 17 to 19. Between the two meetings, there were many updates related to TB drug development. Additional links to TB R&D are included.

20 Sep 2011

TB R&D Weekly Update: Zinc Used by Host to Fight TB

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This week, we provide an brief overview of research supported by CNRS, INSERM, Institut Pasteur and other donors providing new evidence of the role of Zinc in the body’s immune response to intracellular infection by M.tb. and the microbe’s strategy to subvert this defense. Additional links to TB R&D news are included.

8 Sep 2011

TB R&D Weekly Update: TB Drug Updates in Future Medicinal Chemistry

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Last week we posted information about two special issues of Future Medicinal Chemistry focused on neglected diseases. Future Medicinal Chemistry (September 2011, Volume 3, Number 11) have a few articles on tuberculosis drug development. Additional links to TB R&D news are included.

1 Sep 2011

New TB Materials and Tools Available!

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Over the last week, some announcements have been released concerning new tools, publications and meeting materials that may be of value to the TB community including materials from the WGND sponsored “Essentiality of Pyrazinamide” Workshop, an interactive map of clinical trials from PACTR, and a new Collaborative Framework for Care and Control of Tuberculosis and Diabetes from the WHO and The Union.

30 Aug 2011
by Working Group

Posted in Front Lines of TB R&D, TB News

TB R&D Weekly Update: Future Medicinal Chemistry Features Neglected Diseases

fmccover

The August and September issues of Future Medicinal Chemistry will focus on neglected diseases including tuberculosis. The issue includes articles from TB researchers including Ann Ginsberg and Takushi Kaneko. Additional links to TB R&D news are included

4 Aug 2011
by Working Group

Posted in Action, TB News, TB Treatment

Report: The Millenium Development Goals 2011

MDGs2011 pic

The United Nations (UN) released a report on July 12 on the progress made thus far on the 8 Millennium Development Goals (MDGs). The eight MDGs include: end poverty and hunger, universal education, gender equality, child health, maternal health, combat HIV/AIDS, environmental sustainability, and global partnership. Key highlights and additional coverage on the report are included.

TB R&D Weekly Update: Some Multidrug-resistant Bacteria More Fit

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This week we have an article by researchers from Portugal that suggests that in the case of resistance conferred by plasmids that in some cases resistant bacteria increases its ability to replicate and overall fitness compared to susceptible bacteria. This may complicate research and control efforts to address the rising problem of multi-drug resistance. Additional links to TB R&D News are included.

27 Jul 2011
by Working Group

Posted in Action, TB News, TB Treatment, Uncategorized

News from the TB Treatment Field

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Recent articles from around the globe related to governments addressing problems with providing treatment services to those with tuberculosis

12 Jul 2011
by Working Group

Posted in TB Drug Development, TB News

TB R&D Weekly Update: Early bactericidal activity of OPC-67683

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This week, we review a recent article published in the July issue of IJTLD on the TB drug candidate OPC-67683 whose new generic name is delamanid. Diacon, et al., present data showing that delamanid is safe, well-tolerated with significant early bactericidal activity. Links to additional TB R&D news is included.