
In the July 7 issue of the New England Journal, two articles and an editorial on latent TB and TB prevention are published. One study discusses positive results on a treatment for latent TB in HIV-infected persons. The other study discusses negative findings that isoniazid is not effective in latent treatment of tuberculosis in children regardless of HIV status. A link to MedPage Today is included that provides a good overview of these studies and the editorial. Additional TB R&D News Links also are included.
On June 6, 2011, the Stop TB Partnership launched the initiative Time to Act–Save a Million Lives by 2015 at the UN Headquarters at a reception hosted by Ray Chambers, the UN Secretary-General’s Special Envoy for Malaria and UN MDG Advocate. If you would like to respond to this call to action, visit www.action.org.
Dr. Michael D. Iseman, a world renowned pulmonologist and leading expert on tuberculosis has joined Oxford Immunotec as the Senior Scientific Advisor. In May 2010, the WGND had the honor of interviewing Dr. Iseman in our “Voices from the Fight to Stop TB” series. We congratulate Dr. Iseman on is new position!
The MTBVAC01 vaccine candidate, developed to protect people against tuberculosis, will start Phase I clinical trials early in 2012. This was announced by the Spanish biopharmaceutical company Biofabri. The candidate was developed by the University of Zaragoza, Spain and is part of the international portfolio of TuBerculosis Vaccine Initiative (TBVI). Tuberculosis causes almost two million deaths per year.
Dr. Peter Andersen, the Vice President of Vaccine Research and Development at Statens Serum Institut (SSI) and TBVI partner, has been awarded the prestigious Novo Nordisk prize for his work in TB vaccine development. The WGND interviewed Dr. Andersen for our TB R&D Weekly Update on March 8. Congratulations to Dr. Andersen! For full story, [...]
The first detailed study of the private tuberculosis (TB) drug market, published on May 4th, in the PLoS ONE journal, finds that the market is surprisingly large, and has irregular practices that could be driving treatment failures and contributing to the emergence of multidrug-resistant TB (MDR-TB).
CNN featured TB diagnostic Xpert MTB/RIF in its Inside Africa program and looked at the implementation of Xpert MTB/RIF in Uganda. In addition, the CORE Group hosted an online presentation on Xpert MTB/RIF from Elizabeth Talbot, Associate Professor of Infectious Diseases and International Health at Dartmouth Hitchcock Medical Center, and Medical Scientist, FIND: Foundation for Innovative New Diagnostics. Results of a survey of their TB Working Group listserv also is included.