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Working Group on New TB Drugs

Stop TB Partnership

TB R&D Update: Scientists discover a new resistance mechanism to second line drug Bedaquiline

Janssen

Scientists at Janssen Pharmaceutica have characterized a novel resistance mechanism to Bedaquiline (BDQ), a second line antibiotic for the treatment of MDR-TB.

TB R&D Update: Tuberculosis enzyme, isocitrate lyase, grants bacterium protection against antibiotic treatment

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A new study published by Dr. Kyu Rhee’s laboratory at the Weill Cornell Medical College details a potential mechanism driving Mycobacterium tuberculosis’ intrinsic resistance to antibiotics.

11 Jun 2014
by Working Group

Posted in Action, Announcements, TB News, Uncategorized

Panel of TB experts releases report calling for the prioritization of tuberculosis R&D

CSIS Logo

The Center for Strategic and International Studies (CSIS) released six policy reports detailing the domestic and global health burden of tuberculosis and recommendations for the United States government to combat the disease.

Kick TB Campaign Expands to Brazil

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The Kick TB Campaign is a unique project that uses the World’s most popular sport to educate and engage young people in the effort to stop the spread of tuberculosis. First inaugurated in South Africa during the 2010 World Cup, Kick TB has expanded to Brazil, the host country of the 2014 World Cup.

TB R&D Update: Podcast Interview with Dr. Iwao Ojima

Dr. Iwao Ojima

Dr. Iwao Ojima is a Distinguished Professor and Director of the Institute of Chemical Biology and Drug Discovery at Stony Brook University. In this interview, Dr. Ojima discusses the work his lab has been doing on tri-substituted benzimidazole compounds that inhibit TB growth.

Delamanid approved for use in the European Union

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The European Commission has approved delaminid (Deltyba) for use in patients suffering from MDR-TB.

27 Mar 2014
by Working Group

Posted in Announcements, TB News, TB Pediatrics, Uncategorized

TB Alliance makes series of announcements regarding new initiatives to combat childhood TB

TBAlliance

TB Alliance, an international non-profit whose mission is to develop better and more affordable drugs against tuberculosis, made three announcements on World TB Day demonstrating their commitment to combating childhood TB.

UPDATE Exposed: Aeras’ Film Series on Tuberculosis

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Release of Chapter 1 of EXPOSED occured the week of May 20. EXPOSED is a four-part series of short films that tell the story of the deadly global epidemic of tuberculosis. The series will portray the struggles of four inspiring individuals – an MDR-TB survivor, a TB doctor, a clinical trial volunteer, and a TB vaccine researcher – bringing viewers to the forefront of the race against tuberculosis. Click article to view the trailer and Chapter 1 “The Global Epidemic”.

Immunotherapeutic Vaccines, TB and China: Interview with Dr. Douglas Lowrie

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This week we highlight an interview with Dr. Douglas Lowrie, a Senior Research Fellow at Fudan University’s Shanghai Public Health Clinical Center in China. He discusses the extent of the problem of TB in China and innovative research on enhancing TB treatment using immunotherapeutic vaccines.

27 Aug 2012
by Working Group

Posted in Announcements, TB News, Uncategorized

TB Set to Achieve Major Millennium Development Goal by 2015

Click here to read full report.

The 2012 Millennium Development Report was just released highlighting progress made to date. Great strides have been made in HIV and TB from the year 1990 (see below). The Global Plan to Stop TB issued by the Stop TB Partnership is set within the context of the Millennium Development Goals (MDGs).