Welcome to the Working Group on New TB Drugs Blog
TB R&D Weekly Update: ICAAC and TB Drug Clinical Workshop
On September 16, the 4th International Workshop on Clinical Pharmacology of Tuberculosis Drugs was held adjacent to the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) which was held from September 17 to 19. Between the two meetings, there were many updates related to TB drug development. Additional links to TB R&D are included.
TB R&D Weekly Update: Zinc Used by Host to Fight TB
This week, we provide an brief overview of research supported by CNRS, INSERM, Institut Pasteur and other donors providing new evidence of the role of Zinc in the body’s immune response to intracellular infection by M.tb. and the microbe’s strategy to subvert this defense. Additional links to TB R&D news are included.
WHO Alarmed by Rising Rates of Drug-Resistant TB in Europe
Yesterday, BBC News published an article on the WHO Plan entitled “Consolidated action plan to prevent and combat multidrug- and extensively drug-resistant tuberculosis in the WHO European Region 2011–2015.” The plan outlines the problem as well as a solution that could save 120,000 lives if successful.
REGISTRATION OPEN! WGND Annual Meeting and Dinner 2011
We invite you to join us for the Stop TB Partnership Working Group on New Drugs’ Annual Meeting 2011 at the Grand Palais in Lille, France, on October 26. Also, we are sponsoring a dinner on October 25 at Le Barbue d’Anvers in Lille to allow our Sub-groups (Biology/Targets, Candidates, Critical Knowledge and Tools, and Clinical Trial Capacity) to meet and plan for activities for 2012. Please make plans to attend both events.
TB R&D Weekly Update: TB Drug Updates in Future Medicinal Chemistry
Last week we posted information about two special issues of Future Medicinal Chemistry focused on neglected diseases. Future Medicinal Chemistry (September 2011, Volume 3, Number 11) have a few articles on tuberculosis drug development. Additional links to TB R&D news are included.
New TB Materials and Tools Available!
Over the last week, some announcements have been released concerning new tools, publications and meeting materials that may be of value to the TB community including materials from the WGND sponsored “Essentiality of Pyrazinamide” Workshop, an interactive map of clinical trials from PACTR, and a new Collaborative Framework for Care and Control of Tuberculosis and Diabetes from the WHO and The Union.
TB R&D Weekly Update: Future Medicinal Chemistry Features Neglected Diseases
The August and September issues of Future Medicinal Chemistry will focus on neglected diseases including tuberculosis. The issue includes articles from TB researchers including Ann Ginsberg and Takushi Kaneko. Additional links to TB R&D news are included
Global Fund Round 11 Launched!
The Stop TB Partnership has provided information and references to help partners to prepare a successful proposal to The Global Fund to Fight HIV/AIDS, Tuberculosis, and Malaria. The call for Round 11 applications was released on August 15. Go to http://www.stoptb.org/global/tbfriends/ to get more information.
TB R&D Weekly Update: New Target Identified for Pyrazinamide
This week we highlight an article published out of Ying Zhang’s laboratory at Johns Hopkins University that puts forth a new model for the mode of action of pyrazinamide (PZA) and as well as suggest trans-translation as a potential target to consider in the development of new drugs for TB. Additional links to TB R&D news are included.
Posted in Regulations and Guidelines, TB Prevention and Control Strategies, TB Treatment
Updated WHO guidelines on Drug-Resistant TB
The WHO issued updated guidelines on the programmatic management of drug-resistant TB on August 4, 2011 online in the European Respiratory Journal.
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Toppix TB News- Calif. Man Is Criminally Charged to Force Compliance with Tuberculosis Treatment Plan 18 May 2012
- Indian Hospital patients share stories to help heal 17 May 2012
- West Springfield women honored for working with immigrants to prevent tuberculosis 15 May 2012
- MSF says additional resources needed to improve ART access in Burma 11 May 2012
- World disease fund gets added $1.6 bln shot in arm 9 May 2012
