Welcome to the Working Group on New TB Drugs Blog
TB R&D Weekly Update: TDR Tuberculosis Strain Bank
This week we highlight an article looking at the TDR Tuberculosis Strain Bank and its utility. Additional links to TB R&D news are included.
International TB Research Roadmap Launched!
A plan targeting researchers around the world and providing them with a framework to achieve the research objectives of the the Global Plan to Stop TB 2011-2015 and beyond, towards elimination of TB, was launched on Saturday at the Union World Conference on Lung Health.
TB R&D Weekly Update: Zinc Used by Host to Fight TB
This week, we provide an brief overview of research supported by CNRS, INSERM, Institut Pasteur and other donors providing new evidence of the role of Zinc in the body’s immune response to intracellular infection by M.tb. and the microbe’s strategy to subvert this defense. Additional links to TB R&D news are included.
TB R&D Weekly Update: T-Cell Surface Markers as Potential Biomarkers for TB Treatment
In this week’s article, potential cellular biomarkers are explored in the mouse model with three potential markers: PD-1 and TIM-3 on CD8 T cells and KIRG-1 on both CD4 and CD8 T cells. The search for validated biomarkers that can predict treatment success has been a difficult one. The focus of much of the research on biomarkers has been on serum markers, because of practical reasons and considerations of use in resource-limited settings. Henao-Tamayo, et al., took a different focus looking at markers on the surface of lung T cells. Additional links to TB R&D News are included.
Posted in Front Lines of TB R&D, Funding Opportunities, TB Drug Development, TB News
New Gates Foundation Grant Opportunity–Tuberculosis Biomarkers
The Bill & Melinda Gates Foundation is now accepting letters of inquiry for the new grant program Biomarkers for the Diagnosis of Tuberculosis. Letters of inquiry are being accepted online until March 31, 2011 10:00 am PT.
This Week in TB R&D – 29 June 2010
By far, one of the greatest needs in TB R&D is the identification of biomarkers. The value of biomarkers cannot be overemphasized. Briefly, we will highlight what biomarkers are, how they are used, and describe their importance and potential for significant impact for TB drug discovery.
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Toppix TB News- Editorial: Lives at risk if the U.S. shortchanges Global Fund 4 Feb 2012
- Multidrug-Resistant Tuberculosis - Update 3 Feb 2012
- Multidrug-Resistant Tuberculosis - Update 3 Feb 2012
- WHO says TB in Russia displays highest known drug resistance 3 Feb 2012
- Media outlets examine Global Fund's future as it enters second decade 3 Feb 2012
