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Working Group on New TB Drugs

Stop TB Partnership

4 Feb 2013

TB R&D Weekly Update: TB Vaccine Efficacy Trial Yields Key Insights and Poor Results


The results of the first TB vaccine efficacy trial in over 90 years was released today showing that the vaccine candidate MVA85A when given as a booster did not provide added protection to infants who had already received BCG. The trial adds scientific value to the field and enhances the field’s understanding and ability in conducting large-scale TB vaccine trials. Additional links to TB R&D news are included.

27 Nov 2012
by Working Group

Posted in Events, TB Drug Development, TB News, TB Treatment

Recap from the 43rd Union World Conference in Kuala Lumpur

Visuel 8,5 x 11 inch.indd

The week of November 12th was exciting with the 43rd Union World Conference, the WGND Annual Meeting (will be posting presentations soon), and the Stop TB Coordinating Board Meeting. Included are some news highlights and a listing of webcasts of interesting and presentations relevant for TB drug development and research.

The Growing Landscape of TB Trials: Interview with Dr. Andrew Vernon


This week we highlight an interview with Dr. Andrew Vernon, the Chief, Clinical Research Branch, Division of Tuberculosis Elimination at the U.S. Centers for Disease Control and Prevention (CDC). He discusses the progress made in TB drug development and the growing number of TB trials and trials groups.

Immunotherapeutic Vaccines, TB and China: Interview with Dr. Douglas Lowrie


This week we highlight an interview with Dr. Douglas Lowrie, a Senior Research Fellow at Fudan University’s Shanghai Public Health Clinical Center in China. He discusses the extent of the problem of TB in China and innovative research on enhancing TB treatment using immunotherapeutic vaccines.

Launch of the Good Participatory Practice Guidelines for TB Drug Trials

cptr gpp tb

The Stakeholder and Community Engagement Workgroup of the Critical Path to TB Drug Regimens initiative launches guidelines that will facilitate the involvement of communities and participants in the conduct of TB drug trials.

4 Sep 2012
by Working Group

Posted in Front Lines of TB R&D, TB News, TB Treatment

TB R&D Weekly Update: High Dose Vitamin D May Enhance TB Treatment


This week we highlight a study showing promising results that providing high dose vitamin D supplements along with antibiotics could improve treatment outcomes for TB patients. The abstract and additional news coverage are included, as well as, links to other TB R&D news.

15 Aug 2012

2012 WGND Annual Meeting is Nov 14 in Kuala Lumpur

2010 Annual Meeting

We will have our 2012 Annual Meeting in Kuala, Lumpur on Wednesday, November 14 at the Impiana KLCC Hotel from 13:00 to 17:30. The meeting will be held in conjunction with the 43rd Union World Conference on Lung Health.

11 Apr 2012

TB R&D Update: Strategies for Early and Late Stage Drug Development


This week, we are highlighting two articles published online in the Journal of Infectious Diseases in March. The first article by Coxon, et al., looks at the benefits and limitations of the two main approaches to compound discovery for TB, target-based and phenotypic-based. The second article by Phillips, et al., would like TB clinical trialists to consider new strategies or designs for evaluating TB drug regimens which could alleviate a bottleneck as new drugs and consequently new potential drug combinations move into clinical testing. Additional links to TB R&D publications and news are included.

27 Mar 2012

TB R&D Update: 243rd American Chemistry Society Conference


The 243rd American Chemistry Society National Meeting and Exposition is being held in San Diego, California, from March 26 to March 29. There are several presentations on tuberculosis. Here are the abstracts of a few of the talks. The first item received news coverage and discusses two approved antibiotics that may prove effective in treating TB. Additional links to TB R&D News are included.

23 Mar 2012
by Working Group

Posted in Action, Announcements, Events, TB News

World TB Day! Overview of Events, News and Messages


Saturday, March 24, is officially World TB Day but there has been a stream of activities, publications, news and messages to let the world not forget about this major infectious disease killer that claims millions of lives each year. We present links and summaries of events, publications, messages, and news coverage leading up to World TB Day.