Over the past couple of weeks there have been much discussion and reporting on totally drug-resistant tuberculosis (TDR-TB) based on reports of new cases in India. Here are links to coverage of TDR-TB in India, excerpt from a response by Dr. Nardell who we interviewed last year, and link to the WHO Fact Sheet on TDR-TB. Additional links to TB R&D News are included.
On September 16, the 4th International Workshop on Clinical Pharmacology of Tuberculosis Drugs was held adjacent to the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) which was held from September 17 to 19. Between the two meetings, there were many updates related to TB drug development. Additional links to TB R&D are included.
The first detailed study of the private tuberculosis (TB) drug market, published on May 4th, in the PLoS ONE journal, finds that the market is surprisingly large, and has irregular practices that could be driving treatment failures and contributing to the emergence of multidrug-resistant TB (MDR-TB).
Mohini Bai came to our NGO about 8 years back. She had lost her husband to AIDS and both she and her younger son had also tested positive for HIV. When we asked her to get her elder daughter tested, she kept putting it off as she was really scared that the girl may test positive as well. Finally one morning she brought in her daughter for testing. The girl was in the 4th or 5th standard at the time. We were all relieved when the girl’s test came back negative for HIV.
Eight months into her marriage, Rose Joseph (21, name changed) was diagnosed with tuberculosis (TB) in January. Joseph was hospitalised for a week but when she was discharged, her husband asked her to stay at her parents’ place in Malad, saying he and his family had to travel for a wedding. For two weeks, her husband did not call to check on her. When her mother took her to her husband’s home, her mother-in-law said they didn’t want her in the house because she had TB. “My husband wasn’t even ready to face me. My mattress, bedsheets and other belongings had been burned,” said Joseph.
It may be curable but Tuberculosis (TB) remains a stigma in our country especially for women. Over a lakh Indian women are thrown out of their homes each year because they have TB. NDTV brings you the story of a woman who was deserted by her husband one year after marriage because she was diagnosed with TB. The 21-year-old woman’s only fault was that she was infected with tuberculosis.
The TB Alliance and AstraZeneca announced today at the 2010 BIO International Convention that they have entered into a research collaboration agreement to accelerate the discovery, development and clinical use of drugs against tuberculosis (TB), including drug-resistant strains of the disease. One in five patients with TB are resistant to at least one of today’s standard first-line TB drugs according to the World Health Organization.