Welcome to the Working Group on New TB Drugs Blog
Posted in Front Lines of TB R&D, Voices from the Fight to Stop Tuberculosis, WGND Podcast Series
TB R&D Weekly Update: Podcast interview with Dr. Gyanu Lamicchane
Microbial geneticist Dr. Gyanu Lamichhane of the Johns Hopkins Center for Tuberculosis Research is one of 49 recipients of the New Innovator Award, which is given to promising scientists in the early stages of their careers and is supported directly with $1.5 million in research funding over five years. In this interview, we discuss the award and the related research that lead to the award, as well as, Dr. Lamichhane’s motivation to work with TB. Additional links to TB R&D news are included.
TB R&D Weekly Update: New Target Identified for Pyrazinamide
This week we highlight an article published out of Ying Zhang’s laboratory at Johns Hopkins University that puts forth a new model for the mode of action of pyrazinamide (PZA) and as well as suggest trans-translation as a potential target to consider in the development of new drugs for TB. Additional links to TB R&D news are included.
Posted in Front Lines of TB R&D, TB Drug Development, TB R&D Spotlight Interviews, WGND Podcast Series
TB R&D Weekly Update: Podcast Interview with Eric Nuermberger
In this week”s TB R&D update, the WGND had the opportunity to talk with Dr. Nuermberger on a recent article entitled “PA-824 exhibits time-dependent activity in a murine model of tuberculosis” that we covered in a previous TB R&D Weekly Update. In the interview, Dr. Nuermberger provides an overview of his present research, key results presented in the article, and in vitro and preclinical testing of TB drug regimens. Also, links to additional news in TB R&D are included.
This Week in TB R&D – 15 June 2010
On Friday, June 11th, the Johns Hopkins University Center for Tuberculosis Research hosted their annual scientific meeting and the WGND was there to cover the event. Approximately 100-200 people were present including persons from NIH and small pharmaceutical companies. This annual meeting is an opportunity for the epidemiological, clinical and basic researchers to relate their [...]
TB Researcher William Bishai Named to Head New TB-HIV Institute at Mandela School of Medicine in Durban, South Africa
DURBAN, SOUTH AFRICA (May 26, 2010) – The University of KwaZulu-Natal (UKZN) and the Howard Hughes Medical Institute today announced the appointment of William R. Bishai, M.D., Ph.D., as the first permanent director of the KwaZulu-Natal Research Institute for Tuberculosis and HIV (K-RITH).
Ethionamide: A “new” first-line drug for Tuberculosis?
Developing new TB drugs is inhibited by so many factors – namely: The flow through the TB drug pipeline is slow at best. Despite decades of hard work, we still use the demanding regimen developed 50 years ago – a regimen that requires patients to undergo 6-9 months of treatment consisting of four first-line TB [...]
Jacques Grosset Interview
Since the beginning of my professional life I have been involved in research to improve the control of tuberculosis, mainly by improving treatment of tuberculosis and preventing the development of drug resistance.
Photos from Event to Honor Dr. Jacques Grosset
On November 13, 2009, people gathered at Johns Hopkins University to celebrate the work and life of Dr. Jacques Grosset, a legend in TB research.
Vitamins, Sunshine and Cannibalism: New Partners in the Fight to Stop Tuberculosis
One of the characteristics making M. tuberculosis such an insidious killer is its uncanny ability to thwart many of our best defenses. Whether through hiding itself in our lungs for years or escaping our efforts at treatment through multi-drug resistance, this bug often acts as an exceptional escape artist.
An Interview with Susan Dorman of JHU
Susan Dorman serves on the faculty at Johns Hopkins University in TB Research is also the Medical Director of the Baltimore City TB Clinic. This interview was filmed at JHU on November 13, 2009.
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Toppix TB News- Editorial: Lives at risk if the U.S. shortchanges Global Fund 4 Feb 2012
- Multidrug-Resistant Tuberculosis - Update 3 Feb 2012
- Multidrug-Resistant Tuberculosis - Update 3 Feb 2012
- WHO says TB in Russia displays highest known drug resistance 3 Feb 2012
- Media outlets examine Global Fund's future as it enters second decade 3 Feb 2012
