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Working Group on New TB Drugs

Stop TB Partnership

UPDATE Exposed: Aeras’ Film Series on Tuberculosis

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Release of Chapter 1 of EXPOSED occured the week of May 20. EXPOSED is a four-part series of short films that tell the story of the deadly global epidemic of tuberculosis. The series will portray the struggles of four inspiring individuals – an MDR-TB survivor, a TB doctor, a clinical trial volunteer, and a TB vaccine researcher – bringing viewers to the forefront of the race against tuberculosis. Click article to view the trailer and Chapter 1 “The Global Epidemic”.

4 Feb 2013

TB R&D Weekly Update: TB Vaccine Efficacy Trial Yields Key Insights and Poor Results

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The results of the first TB vaccine efficacy trial in over 90 years was released today showing that the vaccine candidate MVA85A when given as a booster did not provide added protection to infants who had already received BCG. The trial adds scientific value to the field and enhances the field’s understanding and ability in conducting large-scale TB vaccine trials. Additional links to TB R&D news are included.

Immunotherapeutic Vaccines, TB and China: Interview with Dr. Douglas Lowrie

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This week we highlight an interview with Dr. Douglas Lowrie, a Senior Research Fellow at Fudan University’s Shanghai Public Health Clinical Center in China. He discusses the extent of the problem of TB in China and innovative research on enhancing TB treatment using immunotherapeutic vaccines.

7 Jun 2012
by Working Group

Posted in Announcements, TB Drug Development, TB News

TB R&D Weekly Update: Delamanid Shows Promise against Multidrug-Resistant TB

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This week, efficacy data from the recently completed Phase 2 randomized placebo-controlled trial in MDR patients evaluating delamanid with background treatment compared to placebo with background treatment was published yesterday in the New England Journal of Medicine. Delamanid (OPC-67683) is a new agent derived from the nitro-dihydro-imidazooxazole class of compounds that inhibits mycolic acid synthesis. The abstract and overview of news coverage are presented, as well as, additional links to TB R&D news.

25 May 2012

TB R&D Weekly Update: Expanding Our Options for TB Treatment

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For this week’s update, we will highlight three recent articles that look at repurposing and optimizing drugs already on the market or looking at novel targets and drug classes for TB. Additional links to TB R&D news are included.

27 Mar 2012

TB R&D Update: 243rd American Chemistry Society Conference

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The 243rd American Chemistry Society National Meeting and Exposition is being held in San Diego, California, from March 26 to March 29. There are several presentations on tuberculosis. Here are the abstracts of a few of the talks. The first item received news coverage and discusses two approved antibiotics that may prove effective in treating TB. Additional links to TB R&D News are included.

23 Mar 2012
by Working Group

Posted in Action, Announcements, Events, TB News

World TB Day! Overview of Events, News and Messages

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Saturday, March 24, is officially World TB Day but there has been a stream of activities, publications, news and messages to let the world not forget about this major infectious disease killer that claims millions of lives each year. We present links and summaries of events, publications, messages, and news coverage leading up to World TB Day.

21 Mar 2012
by Working Group

Posted in Announcements, Events, TB Drug Development, TB News

World TB Day Coverage: New Combo TB Drug Trial Announced

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During the “Cure All: A briefing on the status of the most promising new TB drugs research” sponsored by the Critical Path to New TB Drug Regimens (CPTR) on Monday, March 19, Dr. Mel Spigelman, CEO & President, of TB Alliance announced the launch of the NC002 trial, a combination drug trial that establishes a new pathway to TB and multi-drug resistant TB treatment. The meeting also involved high-level officials from U.S. agencies that support TB research including Anthony Fauci (Director, NIAID/NIH), Janet Woodcock (Director, CDER/FDA), and Robert Clay (Deputy Assistant Administrator, Global Health Bureau/USAID).

8 Dec 2011
by Heather_Ignatius

Posted in Action, Announcements, Front Lines of TB R&D, TB News

4th Annual G-FINDER Survey Released

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Today, the fourth annual G-FINDER survey tracking funding for research and development of neglected disease technologies was released. This year’s report shows that funding for product development is on the decline and product development partnerships (PDPs) have been particularly hard hit, as eight of the top twelve public donors cut their funding in 2010. Now is a time of tremendous opportunity, with dozens of potential products within the reach of patients–donors must commit to taking them across the finish line.

3 Nov 2011
by Working Group

Posted in Announcements, Front Lines of TB R&D, TB News

International TB Research Roadmap Launched!

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A plan targeting researchers around the world and providing them with a framework to achieve the research objectives of the the Global Plan to Stop TB 2011-2015 and beyond, towards elimination of TB, was launched on Saturday at the Union World Conference on Lung Health.