Organization: 

Instituto de Biologia Molecular y Celular de Rosario

First Name: 

Hugo Cesar

Last Name: 

Gramajo

Country: 

Argentina

E-mail: 

gramajo@ibr-conicet.gov.ar

Phone: 

54-341-4237070

Statement: 

We have been working on the metabolism of lipids and its regulation in mycobacteria for about 15 years and throughout that time we have tried to identify and characterize new targets and new compounds that could kill M. tuberculosis. The last 5 years we also engaged with GSK to do HTS with their library of compounds. Recently we also carried out identification of ACCase inhibitors through ELT. We are really motivated to deeply understand lipid homeostasis on M. tb and to validate them as good targets for drug development. Finally we have persued in the identification of new ACCase inhibitors and found new compounds that inhibit those enzymes and kill M. tuberculosis. We will be really interested in actively participating of your institution to learn more about TB and drug development and to contribute with our knowledge as much as we can.

Allow Contact: