News about 'TB Prevention and Control Strategies'

Click here for full report A report entitled “An Evaluation of Drug-resistant TB Treatment Scale-up” was issued by the Médecins Sans Frontières (MSF), Partners in Health (PIH), and Treatment Action Group (TAG) on 7 July, 2011 and looks at the factors contributing to the slow progress of efforts to...

In the July 7 issue of the New England Journal, two articles and an editorial on latent TB and TB prevention are included: Articles Martinson NA, et al “New regimens to prevent tuberculosis in adults with HIV infection” N Engl J Med 2011; 365: 11-20. Madhi SA, et al “Primary isoniazid prophylaxis...

These are the facts (source: Time to Act-Save a million lives by 2015 brochure ) : At least one out of three people in the world has latent TB infection, which increases the risk of becoming ill with TB. People living with HIV have an estimated 20 to 30 times greater risk of developing active TB...

Dr. Armand Van Deun Summary: This week’s interview is with Dr. Armand Van Deun who was the recipient of the 2010 Stop TB Partnership-Kochon Foundation prize . Last year, Dr. Van Deun, et al., published an article in the American Journal of Respiratory and Critical Care Medicine entitled “ Short,...

The first detailed study of the private tuberculosis (TB) drug market, published on May 4 th , in the PLoS ONE journal, finds that the market is surprisingly large, and has irregular practices that could be driving treatment failures and contributing to the emergence of multidrug-resistant TB (MDR-...

Lienhardt C, Cook SV, Burgos M, Yorke-Edwards V, Rigouts L, Anyo G, Kim SJ, Jindani A, Enarson DA, Nunn AJ; Study C Trial Group. Efficacy and safety of a 4-drug fixed-dose combination regimen compared with separate drugs for treatment of pulmonary tuberculosis: the Study C randomized controlled...

Monedero I, Caminero JA. Evidence for promoting fixed-dose combination drugs in tuberculosis treatment and control: a review. Int J Tuberc Lung Dis. 2011 Apr;15(4):433-9. In this week’s article, Monedero and Caminero conduct a critical review of research on the use of fixed-dosed combinations (FDCs...

Frigati LJ, Kranzer K, Cotton MF, Schaaf HS, Lombard CJ, Zar HJ. The impact of isoniazid preventive therapy and antiretroviral therapy on tuberculosis in children infected with HIV in a high tuberculosis incidence setting. Thorax. 2011 Apr 2. [Epub ahead of print] This week, the focus is on...

The Médecins Sans Frontières and The Union will release on World TB Day a new report entitled “DR-TB drugs under the microscope” outlining drugs currently available to treat drug-resistant tuberculosis (DR-TB) including product information, sources of the drug, quality status, and price. The...

Chemical Structure of Pyrazinamide Ahmad Z, Fraig MM, Bisson GP, Nuermberger EL, Grosset JH, Karakousis PC. Dose-dependent activity of pyrazinamide in animal models of intracellular and extracellular tuberculosis. Antimicrob Agents Chemother. 2011 Jan 31. [Epub ahead of print] First discovered as...

Aagaard C, Hoang T, Dietrich J, Cardona PJ, Izzo A, Dolganov G, Schoolnik GK, Cassidy JP, Billeskov R, Andersen P. A multistage tuberculosis vaccine that confers efficient protection before and after exposure. Nat Med. 2011 Jan 23. [Epub ahead of print] Claus Aagaard, et al., presented a series of...

New Evidence Showing Patients with TB Have an Increased Risk of Lung Cancer Yu, et al, in China conducted a population-based cohort study to better understand the relationship between tuberculosis (TB) and lung cancer. Analysis of patient care data from the National Health Insurance (NHI) program...

WHO Press Conference Yesterday, Mario Raviglione , Director of Stop TB, and Giorgio Roscigno, CEO of FIND, held a global press conference announcing the World Health Organization’s endorsement of the new rapid diagnostic test Xpert MTB/RIF. If implemented to scale in countries where tuberculosis (...

Starting 1st December 2010, TB REACH is accepting proposals for the second wave of funding for projects that promote early and increased case detection of tuberculosis (TB) cases and ensure their timely treatment, while maintaining high cure rates within National TB Programmes. TB REACH encourages...

New WHO Guidelines On World AIDS day, the WHO Department of HIV/AIDS and the Stop TB Department issued new guidelines showing how people with HIV can be protected from tuberculosis with regular and low-cost preventive medication. This holds great promise for people living with HIV because TB is...