Compound

Imatinib

Names
Imatinib, Glivec, STI571
Chemical Class:
Benzamide
Description

Imatinib is an FDA-approved oral medicine that is currently used to treat cancer. Imatinib is an antineoplastic agent that inhibits the Bcr-Abl fusion protein tyrosine kinase, an abnormal enzyme produced by chronic myeloid leukemia cells that contain the Philadelphia chromosome. It is sold under the name "Glivec". 

Imatinib is currently under investigation as a host-directed therapy for individuals with latent TB infection.