Institute of Materia Medica, CAMS & PUMC
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Publication. August 2021. Guo S, Wang B, Fu L, Chen X, Zhang W, Huang H, Lu Y. In vitro and in vivo activity of oxazolidinone candidate OTB-658 against Mycobacterium tuberculosis  Antimicrob Agents Chemother Aug 16;AAC0097421. doi: 10.1128/AAC.00974-21. Online ahead of print.

Jiang J, Liu Y, Liu X, Zhang D, Huang H, Wang B, Sheng L, Li Y. Simultaneous determination of a novel oxazolidinone anti-tuberculosis OTB-658 and its metabolites in monkey blood by LC-MS/MS. J Chromatogr B Analyt Technol Biomed Life Sci. 2021 Mar 15;1167:122552. doi: 10.1016/j.jchromb.2021.122552. Epub 2021 Jan 18. PMID: 33588346.

OTB-658(N-(((3S,3aS)-8-Fluoro-1-oxo-7-thiomorpholino-3a,4-dihy-dro-1H,3H-benzo[b]oxazolo[3,4-d][1,4]oxazin-3-yl) methyl) acet-amide)

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Institute of Materia Medica, CAMS & PUMC