Phase 2 Clinical Trial Results of Telacebec Published in NEJM

On March 25th, Qurient announced the results of their Phase 2 Clinical Trial  ( number, NCT03563599), which was a prospective, randomized, open-label trial for proof of concept in humans of their novel anti-tuberculosis drug, Telacebec (Q203). The trial involved 61 newly-diagnosed patients with drug-susceptible pulmonary tuberculosis. Patients received a dose of 100 mg, 200 mg, or 300 mg once daily or combination therapy with rifampin, isoniazid, pyrazinamide, and ethambutol (RHZE) as reported in the New England Journal of Medicine. According to the article, increasing doses of telacebec were associated with greater reductions in time to positivity of collected sputum samples, which they used to determine bactericidal activity. 

To read more about this latest trial by Qurient, take a look at their press release on Business Wire or their article published in the New England Journal of Medicine

More News
23 Aug 2022
Last week, the PAN-TB collaboration announced initial plans for a Phase 2 clinical trial evaluating two novel drug regimens to treat Tuberculosis. Sponsored by the Bill and Melinda Gates Foundation, the PAN-TB, or “Project to Accelerate New Treatments for Tuberculosis”, collaboration brings...
4 May 2022
Earlier this week, the World Health Organization (WHO) released a rapid communication which detailed the upcoming changes to the treatment guidance for drug-resistant tuberculosis (DR-TB). These guidelines are used to inform national TB programmes globally on how to treat patients with these...
5 Apr 2022
On April 01, 2022, the Stop TB Partnership launched the second online consultation for the new Global Plan to End TB 2023-2030. Over the years, the Global Plans have been important tools for advocacy and resource mobilization, and served as a reference document for donors and stakeholders. In May...