NC-003-(C-J-Pa-Z) A Phase 2 Trial to Evaluate the Early Bactericidal Activity, Safety and Tolerability of the Following: TMC207 Plus PA-824 Plus Pyrazinamide Plus Clofazimine, TMC207 Plus PA-824 Plus Pyrazinamide, TMC207 Plus PA-824 Plus Clofazimine Alone, TMC207 Plus Pyrazinamide Plus Clofazimine, Pyrazinamide Alone, and Clofazimine Alone; in Adult Patients With Newly Diagnosed, Smear-Positive Pulmonary Tuberculosis.
Compound
Clofazimine
Novartis
Names
Chemical Class:
Riminophenazine
Description
Related Links
- Outcomes of clofazimine for the treatment of drug-resistant tuberculosis: a systematic review and meta-analysis. Dey et al. J Antimicrob Chemother. 2013 Feb;68(2):284-93.
- Bactericidal activity of pyrazinamide and clofazimine alone and in combinations with pretomanid and bedaquiline. Diacon et al. 2015.Am J Respir Crit Care Med. 2015 Apr 15;191(8):943-53.
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