News

TB R&D Weekly Update: Results from Preventative Therapy Trial in SA Miners

At the 19th Conference on Retroviruses and Opportunistic Infections (CROI) in Seattle, results on the Thibela TB preventative therapy trial in South Africa gold miners was presented with mixed outcomes. On one hand, the number of cases in miners in the experimental group who screened negative for TB received daily isoniazid preventative therapy for 9 months was significantly less than miners who did not receive preventative therapy, but the overall incidence was not significantly different between mines in the experimental group and mines in the control group. All miners who screened positive for TB were treated with standard therapy. Due to the nature of their work, miners have a much higher risk of developing active TB then the general population. The research was conducted by the Aurum Institute (Johannesburg, South Africa) and the London School of Hygiene and Tropical Medicine (United Kingdom)

Additional Coverage:

Study deflates hopes for daily TB pill

Five-cent-a-day preventive treatment can reduce TB cases among miners by 63%

TB control in mines disappoints

South Africa sets goal of testing all miners for tuberculosis, getting sufferers treated

Additional TB R&D News:

EpiStem Holdings Plc : Epistem signs tuberculosis channel partner agreement

Combating Childhood Tuberculosis

World Tuberculosis Day around the Bend


More News
23 Aug 2022
The PAN-TB collaboration announced initial plans for a Phase 2 clinical trial evaluating two novel drug regimens to treat Tuberculosis. Sponsored by the Bill and Melinda Gates Foundation, the PAN-TB, or “Project to Accelerate New Treatments for Tuberculosis”, collaboration brings together non-...
4 May 2022
Earlier this week, the World Health Organization (WHO) released a rapid communication which detailed the upcoming changes to the treatment guidance for drug-resistant tuberculosis (DR-TB). These guidelines are used to inform national TB programmes globally on how to treat patients with these...
5 Apr 2022
On April 01, 2022, the Stop TB Partnership launched the second online consultation for the new Global Plan to End TB 2023-2030. Over the years, the Global Plans have been important tools for advocacy and resource mobilization, and served as a reference document for donors and stakeholders. In May...