News about 'Uncategorized'

We invite you to join us for the Stop TB Partnership Working Group on New Drugs’ 2012 Annual Meeting at the Impiana KLCC Hotel in Kuala Lumpur, Malaysia on Wednesday, November 14. Also, we are sponsoring a lunch to allow the Sub-groups (Biology/Targets, Candidates, Critical Knowledge and Tools, and...

Last week we posted information about two special issues of Future Medicinal Chemistry focused on neglected diseases. Future Medicinal Chemistry (September 2011, Volume 3, Number 11) have a few articles on tuberculosis drug development: Diarylquinolines, synthesis pathways and quantitative...

Silva RF, Mendonc SCM, Carvalho LM, Reis AM, Gordo I, Trindade S, Dionisio F. Pervasive Sign Epistasis between Conjugative Plasmids and Drug-Resistance Chromosomal Mutations. PLoS Genetics. 2011 July;7(7):1-10. This week we have an article by researchers from Portugal that suggests that in the case...

Recent articles from around the globe related to governments addressing problems with providing treatment services to those with tuberculosis: A Day in the Life of a TB Worker When Farhad Jameel, case manager at Gwinnett County’s tuberculosis control clinic, arrives at work each morning, he...

Vilchèze C, Baughn AD, Tufariello J, Leung LW, Kuo M, Basler CF, Alland D, Sacchettini JC, Freundlich JS, Jacobs WR Jr. Novel Inhibitors of InhA Efficiently Kill Mycobacterium tuberculosis under Aerobic and Anaerobic Conditions. Antimicrob Agents Chemother. 2011 Aug;55(8):3889-98. Epub 2011 May 31...

In the July 7 issue of the New England Journal, two articles and an editorial on latent TB and TB prevention are included: Articles Martinson NA, et al “New regimens to prevent tuberculosis in adults with HIV infection” N Engl J Med 2011; 365: 11-20. Madhi SA, et al “Primary isoniazid prophylaxis...

Chen TC, Lu PL, Lin CY, Lin WR, Chen YH. Fluoroquinolones are associated with delayed treatment and resistance in tuberculosis: a systematic review and meta-analysis. Int J Infect Dis. 2011 Mar;15(3):e211-6. Epub 2010 Dec 30. Chen, et al., conducted a meta-analysis to ascertain the answer to two...

In addition, other discussions in the policy realm toss around the idea that the government should get a return on the sale of drugs that were developed with federal funds in the face of high drug costs and medical care. This debate surrounding the public sectors role in downstream drug development...

Dr Lucica Ditiu, Executive Secretary of the Stop TB Partnership Dr Lucica Ditiu has been appointed Executive Secretary of the Stop TB Partnership. A native of Romania, Dr Ditiu is a physician and researcher who has devoted her career to improving the lives of people living in communities heavily...

New Evidence Showing Patients with TB Have an Increased Risk of Lung Cancer Yu, et al, in China conducted a population-based cohort study to better understand the relationship between tuberculosis (TB) and lung cancer. Analysis of patient care data from the National Health Insurance (NHI) program...

2010 Annual Meeting Following the guest speakers ( click here to view that recap ), several representatives from companies conducting clinical trials of TB drug candidates presented brief updates on progress made in the clinical development of their candidates. Click the presentation name to...

UNAIDS is conducting a second-round assessment on the impact of the financial crisis on HIV treatment and prevention programmes. The first assessment was carried out in August 2009. Its findings were reflected in the report “Update on the impact of the economic crisis: HIV Prevention and Treatment...