Predict TB (Using Biomarkers to Predict TB Treatment Duration) will identify the set of criteria needed to reduce TB treatment times. The PredictTB project team will enroll up to 620 patients with drug sensitive pulmonary TB in a clinical trial with five collaborating sites in Cape Town, South Africa and four in Henan Province, China. Over five years, the team will test criteria using data from radiographic lung scans, assays of patient body fluids and analysis of bacterial cultures.