Boston University

Boston University's Center for Global Health & Development (CGHD)’s work is driven by a deep commitment to use the power of science to promote social change and improve the health of populations worldwide. The CGHD’s faculty and professional staff currently manage more than 50 research projects and programs in over 20 countries. The Opti-Q study will determine the levofloxacin dose and exposure that achieve the greatest reduction in TB bacterial burden with acceptable tolerability by studying 100 adults with MDR-TB at sites in Peru and South Africa.

EDCTP

The European & Developing Countries Clinical Trials Partnership (EDCTP) aims to accelerate the development of new or improved drugs, vaccines, microbicides and diagnostics against HIV/AIDS, tuberculosis and malaria as well as other poverty-related infectious diseases in sub-Saharan Africa, with a focus on phase II and III clinical trials.

NIAID, NIH, DHHS

The National Institute of Allergy and Infectious Diseases (NIAID) conducts and supports basic and applied research to better understand, treat, and ultimately prevent infectious, immunologic, and allergic diseases. For more than 60 years, NIAID research has led to new therapies, vaccines, diagnostic tests, and other technologies that have improved the health of millions of people in the United States and around the world. NIAID is one of the 27 Institutes and Centers of the National Institutes of Health (NIH) within the U.S. Government's Department of Health and Human Services, .

Bill & Melinda Gates Foundation has awarded EPFL-based non-profit iM4TB $2.45 million for PBTZ169 clinical trials

iM4TB is a non-profit based in EPFL’s Innovation Park. Founded in 2013, its mission is “to develop better and faster-acting medicines to fight TB and therefore bridge the gap between the scientific discovery and the market in order to provide affordable TB treatment to anyone in the world.” 

SPR720 (Fobrepodacin)

February 28, 2022. Results available on Phase 2 in  MAC disease  NCT04553406 

January 4 2022. SperoTherapeutics Press Release:  Spero Therapeutics, Inc. announced that the U.S. Food and Drug Administration (FDA) has lifted the clinical hold on the Phase 2 trial of SPR720, Spero’s investigational oral product candidate being developed for nontuberculous mycobacterial (NTM) disease.

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