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For World TB Day 2024, the WGND is spotlighting a monumental achievement in TB drug research and development: the Global TB Drug Pipeline has never been bigger than it is today. The number of drug candidates being clinically evaluated for use in the treatment of adult pulmonary TB has surpassed that of all previous years. The WGND is tracking 19 drug candidates that have initiated or completed a Phase 1 clinical trial for use in treating Tuberculosis. Most have been or are currently being evaluated in a Phase 2 clinical trial and one has made it to Phase 3. These 19 do...
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2 Feb 2011
5-Jul-2011 - 8-Jul-2011 | Montreal, Quebec, Canada Context High quality diagnostic studies are critical to evaluate new tools, to develop evidence-based policies on TB diagnostics. There is evidence that TB diagnostic trials are poorly conducted and poorly reported. Lack of methodologic rigour in...
31 Jan 2011
Gupta A, Bhosale R, Kinikar A, Gupte N, Bharadwaj R, Kagal A, Joshi S, Khandekar M, Karmarkar A, Kulkarni V, Sastry J, Mave V, Suryavanshi N, Thakar M, Kulkarni S, Tripathy S, Sambarey P, Patil S, Paranjape R, Bollinger RC, Jamkar A; Six Week Extended-Dose Nevirapine (SWEN) India Study Team...
26 Jan 2011
This is part three of our interview with Dr. Hesseling. Click here to view part one . Click here to view part two . Dr. Anneke Hesseling is the Director of the Paediatric TB Research Program at the Desmond Tutu TB Centre at Stellenbosch University in Cape Town, South Africa. She has South African...
24 Jan 2011
Aagaard C, Hoang T, Dietrich J, Cardona PJ, Izzo A, Dolganov G, Schoolnik GK, Cassidy JP, Billeskov R, Andersen P. A multistage tuberculosis vaccine that confers efficient protection before and after exposure. Nat Med. 2011 Jan 23. [Epub ahead of print] Claus Aagaard, et al., presented a series of...
19 Jan 2011
This is part two of our interview with Dr. Hesseling. Click here to view part one . Dr. Anneke Hesseling is the Director of the Paediatric TB Research Program at the Desmond Tutu TB Centre at Stellenbosch University in Cape Town, South Africa. She has South African and US training in Medicine and...
18 Jan 2011
Dr Lucica Ditiu, Executive Secretary of the Stop TB Partnership Dr Lucica Ditiu has been appointed Executive Secretary of the Stop TB Partnership. A native of Romania, Dr Ditiu is a physician and researcher who has devoted her career to improving the lives of people living in communities heavily...
17 Jan 2011
Saunders NJ, Urmi HT, Thomson ML, Doig C, Laurenson IF, Blaxter ML. Stepwise mutation to multiple drug resistance in Mycobacterium tuberculosis in an otherwise stable genetic backgrounddoes not support models of high mutation in the host and emphasizes the need for maintained effective...
12 Jan 2011
Several news agencies reported on an article that appeared in the Canadian Medical Association Journal showing an increase risk of serious side-effects for patients over 65 years old being treated for latent tuberculosis. Compared to untreated patients matched by age, patients 65 years old being...
10 Jan 2011
Ahmad Z, Peloquin CA, Singh RP, Derendorf H, Tyagi S, Ginsberg A, Grosset JH, Nuermberger EL. PA-824 exhibits time-dependent activity in a murine model of tuberculosis. Antimicrob Agents Chemother. 2011 Jan;55(1):239-45. Epub 2010 Oct 11.PMID: 20937781 [PubMed – in process] Researchers testing the...
5 Jan 2011
Dr. Anneke Hesseling is the Director of the Paediatric TB Research Program at the Desmond Tutu TB Centre at Stellenbosch University in Cape Town, South Africa. She has South African and US training in Medicine and Epidemiology and is the PI and co-PI on several large research projects relates to...
3 Jan 2011
New Evidence Showing Patients with TB Have an Increased Risk of Lung Cancer Yu, et al, in China conducted a population-based cohort study to better understand the relationship between tuberculosis (TB) and lung cancer. Analysis of patient care data from the National Health Insurance (NHI) program...
20 Dec 2010
BioVision and the Lilly MDR ‐ TB Partnership create an award for young scientists, in conjunction with TWAS, the academy of sciences for the developing world The BioVision Lilly Award, in conjunction with TWAS, the academy of sciences for the developing world, will honour outstanding scientific...
14 Dec 2010
The Wall Street Journal Health Blog reported that the FDA issued a draft guidance for the drug industry “designed to encourage companies to work in tandem to develop two or more new drugs to be used in combination to treat cancer and infectious diseases, among other illnesses.” This is exciting...
13 Dec 2010
ELIMINATING TB BY 2050: AN ACCELERATED GLOBAL RESEARCH STRATEGY PLEASE PARTICIPATE TO HELP TB RESEARCH MOVING FORWARD As a member of the large TB community, you might well be aware of the fact that research is essential for speeding up progress towards Tuberculosis (TB) elimination by 2050. We need...
8 Dec 2010
Raghuvanshi S, Sharma P, Singh S, Van Kaer L, Das G. Mycobacterium tuberculosis evades host immunity by recruiting mesenchymal stem cells. Proc Natl Acad Sci U S A. 2010 Dec 6. [Epub ahead of print] On the early drug discovery front, this study may provide researchers additional areas to target for...
