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For World TB Day 2024, the WGND is spotlighting a monumental achievement in TB drug research and development: the Global TB Drug Pipeline has never been bigger than it is today. The number of drug candidates being clinically evaluated for use in the treatment of adult pulmonary TB has surpassed that of all previous years. The WGND is tracking 19 drug candidates that have initiated or completed a Phase 1 clinical trial for use in treating Tuberculosis. Most have been or are currently being evaluated in a Phase 2 clinical trial and one has made it to Phase 3. These 19 do...
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13 Jun 2011
Louw GE, Warren RM, Gey van Pittius NC, Leon R, Jimenez A, Pando RH, McEvoy CR, Grobbelaar M, Murray M, van Helden PD, Victor TC. Rifampicin Reduces Susceptibility to Ofloxacin in Rifampicin Resistant Mycobacterium tuberculosis through Efflux. Am J Respir Crit Care Med. 2011 Apr 21. [Epub ahead of...
8 Jun 2011
These are the facts (source: Time to Act-Save a million lives by 2015 brochure ) : At least one out of three people in the world has latent TB infection, which increases the risk of becoming ill with TB. People living with HIV have an estimated 20 to 30 times greater risk of developing active TB...
6 Jun 2011
Dr. Armand Van Deun Summary: This week’s interview is with Dr. Armand Van Deun who was the recipient of the 2010 Stop TB Partnership-Kochon Foundation prize . Last year, Dr. Van Deun, et al., published an article in the American Journal of Respiratory and Critical Care Medicine entitled “ Short,...
2 Jun 2011
Stop TB Partnership – Kochon Prize 2011 Call for Nominations The Stop TB Partnership Kochon Prize supports the global fight against tuberculosis (TB). The Prize, consisting of a medal and US$ 65 000, is awarded once a year to persons, institutions, or organizations that have made a highly...
1 Jun 2011
MIchael D. Iseman Dr. Michael D. Iseman, a world renowned pulmonologist and leading expert on tuberculosis has joined Oxford Immunotec as the Senior Scientific Advisor. To read full story, click here . In May 2010, the WGND had the honor of interviewing Dr. Iseman in our “Voices from the Fight to...
25 May 2011
Operation ASHA is an NGO based out of New Delhi, India and Chicago, USA Summary: Shelly Batra is a renowned gyn & obs surgeon in New Delhi. She has a deep desire to serve the community. She has worked pro-bono for dissemination of medical information with many television stations and newspapers...
24 May 2011
The MTBVAC01 vaccine candidate, developed to protect people against tuberculosis, will start Phase I clinical trials early in 2012. This was announced by the Spanish biopharmaceutical company Biofabri . The candidate was developed by the University of Zaragoza , Spain and is part of the...
24 May 2011
Please take a minute and help us choose a new logo for the Stop TB Partnership’s Working Group on New Drugs (WGND). Since our inception in 2001, the WGND has evolved and expanded greatly. Through our membership and activities, we have been able to contribute to the critical collaborations and...
23 May 2011
Henao-Tamayo M, Irwin SM, Shang S, Ordway D, Orme IM. T lymphocyte surface expression of exhaustion markers as biomarkers of the efficacy of chemotherapy for tuberculosis. Tuberculosis (Edinb). 2011 Apr 27. [Epub ahead of print] In this week’s article, potential cellular biomarkers are explored in...
18 May 2011
Notice from the Stop TB Partnership: We are writing to encourage you to sign the Call to Action on Childhood TB. The call was an outcome of an international meeting organized jointly by the European Centre for Disease Prevention and Control (ECDC) and the Stop TB Partnership’s Childhood TB Subgroup...
16 May 2011
Dr. Edward Nardell, Partners in Health Summary: This week, we feature an interview with Dr. Edward Nardell who is a pulmonologist with a special interest in tuberculosis; trained in pulmonary medicine at Massachusetts General Hospital with additional research training at Boston University School of...
11 May 2011
Dr. Mark Cotton is Director of Children’s Infectious Diseases Clinical Research Unit (KID-CRU) at University of Stellenbosch in Cape Town, South Africa. Pediatric TB has emerged as a broad priority only in more recent years, though the University of Stellenbosch / Tygerberg Hospital team has been...
10 May 2011
Dr. Bernard Fourie Summary: The WGND had the opportunity to interview Dr. Bernard Fourie who is head of Medicine in Need-South Africa (MEND-SA). In addition, Dr. Fourie is an Extraordinary Professor of Medical Microbiology at the University of Pretoria, South Africa. In the interview, we discuss...
5 May 2011
Dr. Peter Andersen, the Vice President of Vaccine Research and Development at Statens Serum Institut (SSI) and TBVI partner, has been awarded the prestigious Novo Nordisk prize for his work in TB vaccine development. The WGND interviewed Dr. Andersen for our TB R&D Weekly Update on March 8...
3 May 2011
The first detailed study of the private tuberculosis (TB) drug market, published on May 4 th , in the PLoS ONE journal, finds that the market is surprisingly large, and has irregular practices that could be driving treatment failures and contributing to the emergence of multidrug-resistant TB (MDR-...
