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News


19 Sep 2011
Botella H, Peyron P, Levillain F, Poincloux R, Poquet Y, Brandli I, Wang C, Tailleux L, Tilleul S, Charrière GM, Waddell SJ, Foti M, Lugo-Villarino G, Gao Q, Maridonneau-Parini I, Butcher PD, Castagnoli PR, Gicquel B, de Chastellier C, Neyrolles O. Mycobacterial p(1)-type ATPases mediate resistance...
13 Sep 2011
Yesterday, BBC News published an article on the WHO Plan entitled “Consolidated action plan to prevent and combat multidrug- and extensively drug-resistant tuberculosis in the WHO European Region 2011–2015.” The plan outlines the problem as well as a solution that could save 120,000 lives if...
12 Sep 2011
We invite you to join us for the Stop TB Partnership Working Group on New Drugs’ Annual Meeting 2011 at the Grand Palais in Lille, France, on October 26. Also, we are sponsoring a dinner on October 25 at Le Barbue d’Anvers in Lille to allow our Sub-groups (Biology/Targets, Candidates, Critical...
7 Sep 2011
Last week we posted information about two special issues of Future Medicinal Chemistry focused on neglected diseases. Future Medicinal Chemistry (September 2011, Volume 3, Number 11) have a few articles on tuberculosis drug development: Diarylquinolines, synthesis pathways and quantitative...
31 Aug 2011
Over the last week, some announcements have been released concerning new tools, publications and meeting materials that may be of value to the TB community including materials from the WGND sponsored “Essentiality of Pyrazinamide” Workshop, an interactive map of clinical trials from PACTR , and a...
29 Aug 2011
Special Focus: Neglected Diseases [PART 1]. Future Medicinal Chemistry. August 2011, Volume 3, Number 10 ( free issue ) Special Focus: Neglected Diseases [PART 2]. Future Medicinal Chemistry. September 2011, Volume 3, Number 11 (not yet released) The August and September issues of Future Medicinal...
17 Aug 2011
The Stop TB Partnership has provided information and references to help partners to prepare a successful proposal to The Global Fund to Fight HIV/AIDS, Tuberculosis, and Malaria . The call for Round 11 applications was released on August 15. Go to http://www.stoptb.org/global/tbfriends/ to get more...
15 Aug 2011
pyrazinamide (PZA) Shi W, Zhang X, Jiang X, Yuan H, Lee JS, Barry CE 3rd, Wang H, Zhang W, Zhang Y. Pyrazinamide Inhibits Trans-Translation in Mycobacterium tuberculosis . Science. 2011 Aug 11. [Epub ahead of print] This week we highlight an article published out of Ying Zhang’s laboratory at Johns...
10 Aug 2011
The WHO issued updated guidelines on the programmatic management of drug-resistant TB on August 4, 2011 online in the European Respiratory Journal . Abstract The production of guidelines for the management of drug-resistant tuberculosis fits the mandate of the World Health Organization (WHO) to...
3 Aug 2011
Click here for full report The United Nations (UN) released a report on July 12 on the progress made thus far on the 8 Millennium Development Goals (MDGs). The eight MDGs include: end poverty and hunger, universal education, gender equality, child health, maternal health, combat HIV/AIDS,...
1 Aug 2011
Silva RF, Mendonc SCM, Carvalho LM, Reis AM, Gordo I, Trindade S, Dionisio F. Pervasive Sign Epistasis between Conjugative Plasmids and Drug-Resistance Chromosomal Mutations. PLoS Genetics. 2011 July;7(7):1-10. This week we have an article by researchers from Portugal that suggests that in the case...
26 Jul 2011
Recent articles from around the globe related to governments addressing problems with providing treatment services to those with tuberculosis: A Day in the Life of a TB Worker When Farhad Jameel, case manager at Gwinnett County’s tuberculosis control clinic, arrives at work each morning, he...
25 Jul 2011
Vilchèze C, Baughn AD, Tufariello J, Leung LW, Kuo M, Basler CF, Alland D, Sacchettini JC, Freundlich JS, Jacobs WR Jr. Novel Inhibitors of InhA Efficiently Kill Mycobacterium tuberculosis under Aerobic and Anaerobic Conditions. Antimicrob Agents Chemother. 2011 Aug;55(8):3889-98. Epub 2011 May 31...
20 Jul 2011
Mike Mandelbaum is Chief Executive of TB Alert, which is the UK’s National and International Tuberculosis charity – the only British charity working solely on fighting TB in the UK and overseas. TB Alert is a young charity, registered in late 1998 and launched at the Houses of Parliament on World...
18 Jul 2011
BiBianco MV , Blanco FC, Imperiale B, Forrellad MA , Rocha RV, Klepp LI , Cataldi AA , Morcillo N, Bigi F. Role of P27 -P55 operon from Mycobacterium tuberculosis in the resistance to toxic compounds. BMC Infectious Diseases. 2011 Jul 16; 11:195. [Epub ahead of print] This week, we present an...

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