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Last week, the PAN-TB collaboration announced initial plans for a Phase 2 clinical trial evaluating two novel drug regimens to treat Tuberculosis. Sponsored by the Bill and Melinda Gates Foundation, the PAN-TB, or “Project to Accelerate New Treatments for Tuberculosis”, collaboration brings together non-profit, philanthropic, and private sector partners for a common mission to develop novel TB medicines that are better-tolerated, shorter in duration, and simpler to use than existing options. The collaboration includes members such as Evotec, GSK, Janssen, Otsuka, TB...
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29 Jul 2013
Source: Bloomberg http://www.bloomberg.com/news/2013-07-26/otsuka-s-drug-resistant-tb-treatment-fails-to-win-ema-nod.html Otsuka’s Drug-Resistant TB Treatment Fails to Win EMA Nod Otsuka Holdings Co. (4578) failed to win the backing of a European Medicines Agency panel for the Delamanid medicine...
16 Jul 2013
Source: http://www.bloomberg.com/article/2013-07-17/adCNbBPYeTyM.html Sequella, a clinical-stage pharmaceutical company commercializing novel antibiotics to treat life-threatening infectious diseases, today announced that it has licensed Pfizer Inc’s exclusive worldwide rights to develop and...
9 Jul 2013
Yesterday, the US National Public Radio posted online two insightful pieces on tuberculosis. What It Takes To Cure Drug-Resistant Tuberculosis Treating The ‘Body And Soul’ In A Russian TB Prison Please check it out and pass along.
8 Jul 2013
Enrollment has begun for a ground-breaking clinical program exploring the use of delamanid in paediatric multidrug-resistant tuberculosis (MDR-TB) . Otsuka is the first company to perform a trial among this population for regulatory approval. The programme will also evaluate the bioequivalence of a...
30 Jun 2013
Click here to access full report Source: Treatment Action Group The Tuberculosis Treatment Pipeline June 2013 Better than Ever Is Not Good Enough By Erica Lessem Introduction In December 2012, tuberculosis (TB) treatment reached a historic landmark with the first approval by a stringent regulatory...
23 Jun 2013
We invite you to join us for the “Targets for Tomorrow” satellite workshop hosted by the WGND Biology/Targets Subgroup on Monday, July 22, 2013 from 2 p.m. to 4:30 p.m. at the Renaissance Tuscany Il Ciocco Resort , Lucca (Barga), Italy. The workshop is held in conjunction with the Gordon Conference...
12 Jun 2013
From the Stop TB Parntership News: The World Health Organization (WHO) has issued interim guidance on the use of bedaquiline, a new tuberculosis drug, for the treatment of multidrug-resistant tuberculosis (MDR-TB). Bedaquiline was granted accelerated approval by the United States Food and Drug...
22 May 2013
Vilchèze C, Hartman T, Weinrick B, and Jacobs W. Mycobacterium tuberculosis is extraordinarily sensitive to killing by a vitamin C-induced Fenton reaction . Nature Communications. 2013 May 21; 4(1881). doi:10.1038/ncomms2898 Abstract: Drugs that kill tuberculosis more quickly could shorten...
14 May 2013
Update: Release of Part 1 of EXPOSED scheduled for the week of May 20. Contact jrosen@aeras.org if you would like to host a screening event or get more information. EXPOSED is a four-part series of short films that tell the story of the deadly global epidemic of tuberculosis. The series will...
25 Apr 2013
Treatment Action Group (TAG) recently released its Spring 2013 issue of tagline, which contains three articles about TB research that might be of interest to you– 1) on rifapentine research and access , 2) on adaptive clinical trial designs , and 3) on pediatric drug development needs . The full...
15 Apr 2013
MSF Scientific Day 2013 will be streamed live online from the Royal Society of Medicine, London, UK, from 09.00am – 06.00pm (GMT+1) on 10 th May 2013 http://www.msf.org.uk/Scientific_Day.aspx MSF Scientific Day is a unique opportunity to showcase medical and scientific research carried out in MSF...
15 Apr 2013
The Center for Health Market Innovations (CHMI) has compiled profiles on over 1,200 programs and counting. The database categorizes programs into the following types: Organizing Delivery –Programs that reduce fragmentation and informality of health care delivery Financing Care –Programs that...
26 Mar 2013
Click to access links and audio from Lancet ID TB Edition Executive Summary To commemorate World TB Day 2013, The Lancet Infectious Diseases publishes a Series of papers on tuberculosis, a disease that has long plagued human beings and was declared a global emergency in 1993 by WHO. Without...
19 Mar 2013
World TB Day is celebrated on March 24 and there is a lot going on during this week and next to highlight the continued problem of TB in the world and the solutions to address the problem. Below is a list of publications, news items, events, and links related to TB and World TB Day 2013. EVENTS...
3 Feb 2013
The results of the first TB vaccine efficacy trial in over 90 years was released today showing that the vaccine candidate MVA85A when given as a booster did not provide added protection to infants who had already received BCG. The trial adds scientific value to the field and enhances the field’s...
