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For World TB Day 2024, the WGND is spotlighting a monumental achievement in TB drug research and development: the Global TB Drug Pipeline has never been bigger than it is today. The number of drug candidates being clinically evaluated for use in the treatment of adult pulmonary TB has surpassed that of all previous years. The WGND is tracking 19 drug candidates that have initiated or completed a Phase 1 clinical trial for use in treating Tuberculosis. Most have been or are currently being evaluated in a Phase 2 clinical trial and one has made it to Phase 3. These 19 do...
News
19 Mar 2013
World TB Day is celebrated on March 24 and there is a lot going on during this week and next to highlight the continued problem of TB in the world and the solutions to address the problem. Below is a list of publications, news items, events, and links related to TB and World TB Day 2013. EVENTS...
3 Feb 2013
The results of the first TB vaccine efficacy trial in over 90 years was released today showing that the vaccine candidate MVA85A when given as a booster did not provide added protection to infants who had already received BCG. The trial adds scientific value to the field and enhances the field’s...
5 Jan 2013
Press Release from FDA can be found at http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm333695.htm . Press Release from Janssen is below. FDA Grants Accelerated Approval for SIRTURO™ (bedaquiline) as Part of Combination Therapy to Treat Adults with Pulmonary Multi-Drug Resistant...
12 Dec 2012
Multidrug-Resistance Tuberculosis: No Promises from MSF Access Campaign on Vimeo . Patients with tuberculosis must undergo lengthy, arduous treatment regimens in the best of times. When stricken with multidrug-resistant tuberculosis, or MDR-TB, however, the road back to health is even more...
28 Nov 2012
Yesterday, Nov. 28th, the FDA Ant-infective Drug Advisory Committee voted to recommend Janssen ‘s Bedaquiline for accelerated approval for the treatment of MDR tuberculosis. You can access materials from the meeting at http://www.fda.gov/AdvisoryCommittees/Calendar/ucm321011.htm . The sponsor and...
26 Nov 2012
The week of November 12th was exciting with the 43rd Union World Conference, the WGND Annual Meeting (will be posting presentations soon), and the Stop TB Coordinating Board Meeting. Below are some news highlights and a listing of webcasts of interesting and presentations relevant for TB drug...
21 Oct 2012
This week we highlight an interview with Dr. Andrew Vernon, the Chief, Clinical Research Branch, Division of Tuberculosis Elimination at the U.S. Centers for Disease Control and Prevention (CDC). He discusses the progress made in TB drug development and the growing number of TB trials and trials...
16 Oct 2012
Click here to read full report. The WHO released the Global Tuberculosis Report 2012 today. The main take home points are: In the space of 17 years, 51m people were successfully treated for TB saving 20m lives. TB rates worldwide are decreasing but the overall burden remains huge with drug-...
10 Oct 2012
This week we highlight an interview with Dr. Douglas Lowrie, a Senior Research Fellow at Fudan University’s Shanghai Public Health Clinical Center in China. He discusses the extent of the problem of TB in China and innovative research on enhancing TB treatment using immunotherapeutic vaccines.
4 Oct 2012
Click here to read the full document. Launch of the Good Participatory Practice Guidelines for TB Drug Trials The Stakeholder and Community Engagement Workgroup of the Critical Path to TB Drug Regimens initiative launches guidelines that will facilitate the involvement of communities and...
3 Sep 2012
Anna K. Coussensa, Robert J. Wilkinson, Yasmeen Hanifa, Vladyslav Nikolayevskyy, Paul T. Elkington, Kamrul Islam, Peter M. Timms, Timothy R. Venton, Graham H. Bothamley, Geoffrey E. Packe, Mathina Darmalingam, Robert N. Davidson, Heather J. Milburn, Lucy V. Baker, Richard D. Barker, Charles A. Mein...
28 Aug 2012
On September 5 and 6, 2012, the “Demystifying Pyrazinamide – Challenges and Opportunities” Workshop will be held at Johns Hopkins University and is sponsored by National Institute of Allergy and Infectious Diseases, Bill and Melinda Gates Foundation, Johns Hopkins University Center for AIDS...
26 Aug 2012
Click here to read full report. The 2012 Millennium Development Report was just released highlighting progress made to date. Great strides have been made in HIV and TB from the year 1990 (see below). The Global Plan to Stop TB issued by the Stop TB Partnership is set within the context of the...
14 Aug 2012
We invite you to join us for the Stop TB Partnership Working Group on New Drugs’ 2012 Annual Meeting at the Impiana KLCC Hotel in Kuala Lumpur, Malaysia on Wednesday, November 14. Also, we are sponsoring a lunch to allow the Sub-groups (Biology/Targets, Candidates, Critical Knowledge and Tools, and...
31 Jul 2012
Press Release: The Africa Coalition on Tuberculosis (ACT!), whose inception was the result of a Declaration made in Washington, DC, USA in March 2012, kicked off activities at a week-long planning meeting in June in Tirano, Italy. Founding members of the coalition include tuberculosis (TB)...
