Trials

Trial Namesort descending Status
Phase 1 Study to Evaluate Safety, Tolerability, PK, and PK Interactions of TBA-7371 study in development
09-0111 N01AI80024C published
242-07-204 published
A Controlled Trial of a 4-Month Quinolone-Containing Regimen for the Treatment of Pulmonary Tuberculosis. all patients enrolled
A Phase 2 Trial to Evaluate the Efficacy and Safety of Linezolid in Tuberculosis Patients enrolling
A Phase IIa, Open Label Study to Determine the EBA, Extended EBA and Pharmacokinetic Study of LL3858 for the Treatment of Newly Diagnosed Sputum Smear-Positive Pulmonary TB study in development
ACTG 5306 Phase I Evaluating the Safety and Drug Interaction of PA-824, an Investigational Tuberculosis Medication, Together With Efavirenz, Ritonavir-Boosted Lopinavir, or Rifampin enrolling
ACTG 5306 Phase I, Three-Arm Safety, Tolerability, and Pharmacokinetic Interaction Study of PA-824, an Investigational Nitroimidazole for the Treatment of Tuberculosis, Together With Efavirenz, Ritona enrolling
ACTG 5343 Bedaquiline - Delamanid with MBT for MDR enrolling
AZD5847 Randomized, Open Label, Multiple Dose Phase 2a Study of the Early Bactericidal Activity of AZD5847 in Adults With Pulmonary Tuberculosis published
B1171001 published
B1171002 published
B1171003 published
Bedaquiline - Linezolid with OBR MDR (NExT Trial) enrolling
Celecoxib Clinical Study WBA in data analysis
Controlled comparison of two moxifloxacin containing treatment shortening regimens with the standard regimen in pulmonary TB all patients enrolled
Delamanid with OBR for MDR TB in data analysis
Effect of PA-824 and PA-824 plus Moxifloxacin on the QTc Interval in Health Volunteers in data analysis
endTB enrolling
Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis in data analysis
Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis published
Faro-WBA submitted for publication
High-Dose Rifampin published
LMU-IMPH-SQ109-01 published
Meropenem, Faropenem Phase 2 EBA, TASK-001 published
Multiple Dose, Phase 1 published
NC-003 published
NC-005 published
NC001 submitted for publication
NC001 Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis With(J-M-Pa-Z) submitted for publication
NC002
NC002 Phase II Trial to Evaluate the Efficacy, Safety and Tolerability of the Following: PA-824 Plus Moxifloxacin Plus Pyrazinamide in Drug Sensitive and Multi-Drug Resistant Patients
NC003 enrolling
NC003 Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis With Clofazimine (C)-TMC207 (J)-PA-824 (Pa)-Pyrazinamide (Z) enrolling
NC005 enrolling
NCT02836483 A Prospective, Randomized, Open, Active-controlled, Interventional, Exploratory, Phase II Trial of LCB01-0371. enrolling
NexGen EBA enrolling
NIH: A Phase I Open-Label Trial To Investigate the Pharmacokinetic Interaction Between Rifabutin Or Rifampin And A Single Dose Of TMC207 In Healthy Subjects published
Nitzoxanide NZT001 14-day EBA all patients enrolled
Nix-TB (B-Pa-L) in data analysis
PanACEA - RUNMC - HR1 2007.23011.01 published
PanACEA-MAMS-TB-01 published
PanACEA-MAMS-TB-01 all patients enrolled
Pediatric PK and Safety Trial Delamanid in MDR TB enrolling
Perchlozone tablets submitted for publication
Phase 1 Effect of PA-824 and PA-824 plus Moxifloxacin on the QTc Interval in Health Volunteers in data analysis
Phase 2 Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis published
Phase 2 Placebo-controlled, Randomized Study of Oral Immunomodulator in TB and TB/HIV Patients enrolling
Phase 2 Telacebec (Q203) EBA study in development
Phase 2a Study of PBTZ169
PredictTB enrolling
Q203 Phase 1a Q203-TB-PI-US001 in data analysis
Q203 Phase 1b Q203-TB-PI-US002 all patients enrolled
ReDEFINe High-Dose RIF for Meningitis in data analysis
Rifapentine TBTC Study 29 published
RIFASHORT enrolling
Safety and efficacy of blocking IL-4 with pascolizumab in patients receiving standard combination therapy for pulmonary tuberculosis (TB): a randomized, double-blind, placebo-controlled, proof-of-conc enrolling
SimpliciTB enrolling
SimpliciTB-Pa-M-Z) NC-008 study in development
Single Dose, Phase 1 published
SQ109-CP001 published
STAND all patients enrolled
STREAM Trial Stage 2 enrolling
TB Host Directed Therapy (TBHDT) enrolling
TB-PRACTECAL enrolling
TBA 354 Phase 1b Multiple Ascending Dose Study With a Dose Formulation Comparison Cohort to Evaluate the Safety, Tolerability, and Pharmacokinetics of TBA-354 in Healthy Adult Subjects early termination
TBA-354 Phase 1a Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of TBA-354 in Healthy Adult Subjects all patients enrolled
TBTC Study 26: Effectiveness and Tolerability of Weekly Rifapentine/Isoniazid for 3 Months Versus Daily Isoniazid for 9 Months for the Treatment of Latent Tuberculosis Infection published
TBTC Study 30: A Phase I/II Pilot Study for Evaluation of Low Dose, Once Daily, Linezolid Plus Optimized Background Therapy (OBT) Versus Placebo Plus OBT for the Treatment of Multi-drug Resistant Tube submitted for publication
TBTC Study 30PK Linezolid Pharmacokinetics and Pharmacodynamics in the Treatment of Multi-Drug Resistant and Extensively-Drug Resistant Tuberculosis submitted for publication
TBTC Study 31 ACTG 5349 4-month treatment regimens enrolling
TBTC Study 32, Opti-Q enrolling
TBTC Study 33/iAdhere: AdherenceC in data analysis
TMC207-TBC211 study in development
TMC207-TiDP13-208 published
TMC207-TiDP13-C209 published
TMC207TBC1002 published
Traitement du Sida submitted for publication
TRUNCATE-TB enrolling
ZeNix (B-Pa-L) NC-007 enrolling